Tacrolimus (FK506) antibody
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- Target
- Tacrolimus (FK506)
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Reactivity
- Chemical
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- Un-conjugated
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Application
- Enzyme Immunoassay (EIA)
- Characteristics
- Synonyms: Tacrolimus
- Purification
- Purified
- Immunogen
- FK-506-BSA conjugate. Spleen cells from immunised Balb/c mice were fused with cells ofthe Sp2/0 myeloma cell line. Genename: FK-506
- Clone
- FK1
- Isotype
- IgM
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- Application Notes
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0mg/mL
- Buffer
- TRIS buffered saline pH 8.0 containing 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- Tacrolimus (FK506)
- Alternative Name
- FK506
- Target Type
- Chemical
- Background
- FK-506 is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension.Synonyms: FK-506, Tacrolimus
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