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Tacrolimus (FK506) antibody

FK506 Reactivity: Chemical EIA Host: Mouse Monoclonal FK1 unconjugated
Catalog No. ABIN181119
  • Target
    Tacrolimus (FK506)
    Reactivity
    • 4
    • 1
    • 1
    Chemical
    Host
    • 4
    • 3
    Mouse
    Clonality
    • 4
    • 3
    Monoclonal
    Conjugate
    • 7
    Un-conjugated
    Application
    • 6
    • 2
    • 1
    • 1
    • 1
    Enzyme Immunoassay (EIA)
    Characteristics
    Synonyms: Tacrolimus
    Purification
    Purified
    Immunogen
    FK-506-BSA conjugate. Spleen cells from immunised Balb/c mice were fused with cells ofthe Sp2/0 myeloma cell line. Genename: FK-506
    Clone
    FK1
    Isotype
    IgM
  • Application Notes
    ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0mg/mL
    Buffer
    TRIS buffered saline pH 8.0 containing 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    Tacrolimus (FK506)
    Alternative Name
    FK506
    Target Type
    Chemical
    Background
    FK-506 is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension.Synonyms: FK-506, Tacrolimus
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