Tacrolimus (FK506) antibody
Quick Overview for Tacrolimus (FK506) antibody (ABIN181119)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Characteristics
- Synonyms: Tacrolimus
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Purification
- Purified
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Immunogen
- FK-506-BSA conjugate. Spleen cells from immunised Balb/c mice were fused with cells ofthe Sp2/0 myeloma cell line. Genename: FK-506
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Isotype
- IgM
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Application Notes
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0mg/mL
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Buffer
- TRIS buffered saline pH 8.0 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Expiry Date
- 12 months
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- Tacrolimus (FK506)
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Alternative Name
- FK506
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Target Type
- Chemical
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Background
- FK-506 is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension.Synonyms: FK-506, Tacrolimus
Target
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