BMP7 antibody

Catalog No. ABIN181147

This Mouse Monoclonal antibody specifically detects BMP7 in EIA. It exhibits reactivity toward Human.

Quick Overview for BMP7 antibody (ABIN181147)

Target: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BMP7 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Product Details anti-BMP7 Antibody

Specificity: This antibody detects BMP7.

Characteristics: Synonyms: BMP-7, Bone morphogenetic protein 7, OP1, Osteogenic protein 1

Purification: Affinity Chromatography on Protein G

Immunogen: Highly pure (>98%) recombinant Human BMP-7/OP-1

Isotype: IgG1

Application Details

Application Notes: ELISA: In a sandwich ELISA (assuming 100 μL/well), when used as a capture antibody at aconcentration of 2-4 μg/mL, this BMP7 antibody will detect at least 0.1 ng/well ofrecombinant human BMP-7/OP-1 when used with Biotin conjugated anti-BMP-7/OP-1antibody (cat. AP01113BT) as the detection antibody at a concentration of at least 0.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in sterile water to a concentration of 1.0 mg/mL.

Buffer: PBS without preservatives

Preservative: Without preservative

Storage: 4 °C/-20 °C

Storage Comment: The lyophilized antibody is stable at room temperature for one month or at -20 °C forlonger. Following reconstitution it is stable at 2-8 °C for six weeks. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for BMP7

Target: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Alternative Name: BMP7

Background: Bone Morphogenetic Protein 7 (BMP7), also known as osteogenic protein 1 (OP1), is produced from a DNA sequence encoding the human BMP2 signal peptide and human BMP2 propeptide (amino acid residues 1 to 282) fused to the human BMP7 mature subunit (amino acid residues 293 to 431). Mature human BMP7, generated after the proteolytic removal of the signal peptide and the propeptide, is a disulfide linked homodimeric protein, comprised of two 139 amino acid residue subunits. Bone Morphogenetic Proteins (BMP) are members of the TGF beta superfamily of cytokines that affect bone and cartilage formation. Similar to other TGF beta family proteins, BMPs are highly conserved across animal species.Synonyms: BMP-7, Bone morphogenetic protein 7, OP1, Osteogenic protein 1

Gene ID: 655

UniProt: P18075

Pathways: Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance