CD52 antibody

Catalog No. ABIN1819672

This Rat Monoclonal antibody specifically detects CD52 in FACS, IHC, WB, IHC (p), ELISA, IHC (fro), CyTox and IP. It exhibits reactivity toward Human, Monkey and Rhesus Monkey.

Quick Overview for CD52 antibody (ABIN1819672)

Target: CD52

Reactivity: Human, Monkey, Rhesus Monkey

Host: Rat

Clonality: Monoclonal

Conjugate: This CD52 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Cytotoxicity Test (CyTox), Immunoprecipitation (IP)

Clone: YTH34-5

Product Details anti-CD52 Antibody

Specificity: Reacts with the human CD52 antigen, also known as CAMPATH-1. The CD52 antigen is a remarkably small but heavily glycosylated peptide attached to the cell surface membrane via a GPI link. The apparent molecular mass of the native antigen on SDS-PAGE is 25-29kD, considerably reduced following N-glycanase treatment. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable. Humanized versions of CAMPATH-1 specific antibodies are currently in clinical trials for the treatment of a range of lymphoid malignancies ,.

Purification: Protein A purified

Endotoxin Level: Low Endotoxin

Immunogen: Human lymphocytes.

Type of Immunogen: Cells

Isotype: IgG2b

Application Details

Application Notes: Approved: Ctox (50 μg/mL), ELISA, Flo (1:50 - 1:100), IHC, IHC-Fr, IHC-P, IP, WB

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Cytotoxicity: Use human serum as complement source.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CD52

Target: CD52

Alternative Name: CD52

Background: Name/Gene ID: CD52

Synonyms: CD52, Cambridge pathology 1 antigen, CD52 antigen, CD52 Molecule, CDW52, CAMPATH-1 antigen, He5

Gene ID: 1043