CD3 antibody

Catalog No. ABIN1819694

The Mouse Monoclonal anti-CD3 antibody has been validated for FACS, IP, IHC, IHC (fro), IF and IHC (p). It is suitable to detect CD3 in samples from Dog.

Quick Overview for CD3 antibody (ABIN1819694)

Target: CD3

Reactivity: Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CA17-2A12

Product Details anti-CD3 Antibody

Specificity: Recognizes the canine CD3 cell surface antigen, expressed by thymocytes and mature T lymphocytes. CD3 is engaged in the surface expression of the T-cell antigen receptor (TCR) and the signal transduction pathway resulting from MHC ligand binding to the TCR. CD3 is made up of a number of invariant subchains of the immunoglobulin superfamily. Is a valuable flow cytometric and immunohistologic tool for canine lymphoma detection of T-cell origin.

Purification: Protein G purified

Immunogen: Affinity enriched TCR/CD3 membrane proteins isolated from thymocytes and the T cell line CLGL-90.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:25 - 1:50), IF, IHC, IHC-Fr, IHC-P, IP

Comment:

Target Species of Antibody: Dog

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for CD3

Target: CD3

Alternative Name: CD3

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway