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Aggrecan antibody

This Mouse Monoclonal antibody specifically detects Aggrecan in WB, IHC, IP, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human and Cow.
Catalog No. ABIN1834915

Quick Overview for Aggrecan antibody (ABIN1834915)

Target

See all Aggrecan (ACAN) Antibodies
Aggrecan (ACAN)

Reactivity

  • 89
  • 48
  • 34
  • 19
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Cow

Host

  • 91
  • 24
  • 1
  • 1
Mouse

Clonality

  • 84
  • 33
Monoclonal

Conjugate

  • 64
  • 15
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aggrecan antibody is un-conjugated

Application

  • 86
  • 55
  • 37
  • 30
  • 22
  • 14
  • 14
  • 12
  • 8
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone

7D4
  • Specificity

    Recognizes human aggrecan, a proteoglycan and member of the aggrecan/versican proteoglycan family, which forms a major component of the extracellular matrix (ECM) of both cartilage and the central nervous system (CNS). Studies using a panel of core protein-directed antibodies against human aggrecan, revealed the distribution of different aggrecan isoforms within the CNS, and sub-divided the isoforms into clusters 1-5 accordingly. These studies also showed a difference in the relative abundance of these isoforms when comparing brain and cartilage tissues. recognizes epitopes within the N-terminal G1-IGD-G2 region of aggrecan, that has been identified as a cluster 1 isoform.

    No Cross-Reactivity

    Fish, Chicken, Rat (Rattus)

    Purification

    Protein G purified

    Immunogen

    Purified human articular cartilage aggrecan.

    Isotype

    IgG1
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS, 0.09 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    4°C or -20°C, Avoid freeze-thaw cycles.
  • Target

    Aggrecan (ACAN)

    Alternative Name

    Aggrecan

    Background

    Name/Gene ID: ACAN

    Synonyms: ACAN, AGCAN, Aggrecan core protein, Acg1, Aggrecan, CSPG1, CSPGCP, CSPCP, AGC1, Aggrecan 1, Large aggregating proteoglycan, MSK16, SEDK, MCSPG

    Gene ID

    176

    Pathways

    Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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