Aggrecan antibody
Quick Overview for Aggrecan antibody (ABIN1834915)
Target
See all Aggrecan (ACAN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Specificity
- Recognizes human aggrecan, a proteoglycan and member of the aggrecan/versican proteoglycan family, which forms a major component of the extracellular matrix (ECM) of both cartilage and the central nervous system (CNS). Studies using a panel of core protein-directed antibodies against human aggrecan, revealed the distribution of different aggrecan isoforms within the CNS, and sub-divided the isoforms into clusters 1-5 accordingly. These studies also showed a difference in the relative abundance of these isoforms when comparing brain and cartilage tissues. recognizes epitopes within the N-terminal G1-IGD-G2 region of aggrecan, that has been identified as a cluster 1 isoform.
-
No Cross-Reactivity
- Fish, Chicken, Rat (Rattus)
-
Purification
- Protein G purified
-
Immunogen
- Purified human articular cartilage aggrecan.
-
Isotype
- IgG1
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
Target Species of Antibody: Human
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- PBS, 0.09 % sodium azide
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
-
-
- Aggrecan (ACAN)
-
Alternative Name
- Aggrecan
-
Background
-
Name/Gene ID: ACAN
Synonyms: ACAN, AGCAN, Aggrecan core protein, Acg1, Aggrecan, CSPG1, CSPGCP, CSPCP, AGC1, Aggrecan 1, Large aggregating proteoglycan, MSK16, SEDK, MCSPG -
Gene ID
- 176
-
Pathways
- Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
Target
-