ADRM1 antibody (C-Term)

Catalog No. ABIN1881049

This Rabbit Polyclonal antibody specifically detects ADRM1 in WB. It exhibits reactivity toward Human and has been mentioned in 5+ publications.

Quick Overview for ADRM1 antibody (C-Term) (ABIN1881049)

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRM1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB41862

Product Details anti-ADRM1 Antibody

Binding Specificity: AA 368-397, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ADRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 368-397 amino acids from the C-terminal region of human ADRM1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ADRM1 antibody (ABIN1881049)

Mazumdar, Gorgun, Sha, Tyryshkin, Zeng, Hartmann-Petersen, Jørgensen, Hendil, Eissa: "Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13)." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 31, pp. 13854-9, (2010) (PubMed).

Elangovan, Oh, Sukumaran, Wójcik, Yoo: "Functional differences between two major ubiquitin receptors in the proteasome; S5a and hRpn13." in: Biochemical and biophysical research communications, Vol. 396, Issue 2, pp. 425-8, (2010) (PubMed).

Chen, Lee, Finley, Walters: "Structure of proteasome ubiquitin receptor hRpn13 and its activation by the scaffolding protein hRpn2." in: Molecular cell, Vol. 38, Issue 3, pp. 404-15, (2010) (PubMed).

Chen, Hu, Shi, Zhang, He: "[Silencing of Adrm1 by RNA interference suppresses proliferation of colorectal cancer cells]." in: Zhonghua zhong liu za zhi [Chinese journal of oncology], Vol. 31, Issue 11, pp. 815-9, (2010) (PubMed).

Kim, Ha, Kim, Yi, Lee, Choi: "Adrm1 interacts with Atp6v0d2 and regulates osteoclast differentiation." in: Biochemical and biophysical research communications, Vol. 390, Issue 3, pp. 585-90, (2009) (PubMed).

Target Details for ADRM1

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Alternative Name: ADRM1

Background: The protein encoded by this gene is an integral plasma membrane protein which promotes cell adhesion. The encoded protein is thought to undergo O-linked glycosylation. Expression of this gene has been shown to be induced by gamma interferon in some cancer cells. Two transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 42153

NCBI Accession: NP_001268366, NP_001268367, NP_008933, NP_783163

UniProt: Q16186

Pathways: Positive Regulation of Endopeptidase Activity