Amphiphysin antibody (AA 140-168)

Catalog No. ABIN1881055

Product Details anti-Amphiphysin Antibody

Target: Amphiphysin (AMPH)

Binding Specificity: AA 140-168

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Amphiphysin antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AMPH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the Central region of human AMPH.

Clone: RB41814

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Amphiphysin antibody (ABIN1881055)

He, Wu, Wang, Yang, Liao, Zhang: "Toward quantitative characterization of the binding profile between the human amphiphysin-1 SH3 domain and its peptide ligands." in: Amino acids, Vol. 38, Issue 4, pp. 1209-18, (2010) (PubMed).

Liu, He, Yang, Xu: "Applying chemometrics approaches to model and predict the binding affinities between the human amphiphysin SH3 domain and its peptide ligands." in: Protein and peptide letters, Vol. 17, Issue 2, pp. 246-53, (2010) (PubMed).

Zhou, Tian, Chen, Shang: "Modeling and prediction of binding affinities between the human amphiphysin SH3 domain and its peptide ligands using genetic algorithm-Gaussian processes." in: Biopolymers, Vol. 90, Issue 6, pp. 792-802, (2008) (PubMed).

Hou, Zhang, Case, Wang: "Characterization of domain-peptide interaction interface: a case study on the amphiphysin-1 SH3 domain." in: Journal of molecular biology, Vol. 376, Issue 4, pp. 1201-14, (2008) (PubMed).

Target Details for Amphiphysin

Target: Amphiphysin (AMPH)

Alternative Name: AMPH (AMPH Products)

Background: This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.

Molecular Weight: 76257

NCBI Accession: NP_001626, NP_647477

UniProt: P49418