CD3EAP antibody (N-Term)

Catalog No. ABIN1881185

The Rabbit Polyclonal anti-CD3EAP antibody has been validated for WB. It is suitable to detect CD3EAP in samples from Human. There are 4+ publications available.

Quick Overview for CD3EAP antibody (N-Term) (ABIN1881185)

Target: CD3EAP (CD3e Molecule, epsilon Associated Protein (CD3EAP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD3EAP antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB41983

Product Details anti-CD3EAP Antibody

Binding Specificity: AA 54-81, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CD3EAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-81 amino acids from the N-terminal region of human CD3EAP.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-CD3EAP antibody (ABIN1881185)

Guey, García-Closas, Murta-Nascimento, Lloreta, Palencia, Kogevinas, Rothman, Vellalta, Calle, Marenne, Tardón, Carrato, García-Closas, Serra, Silverman, Chanock, Real, Malats: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, (2010) (PubMed).

Vangsted, Klausen, Gimsing, Andersen, Abildgaard, Gregersen, Vogel: "A polymorphism in NFKB1 is associated with improved effect of interferon-{alpha} maintenance treatment of patients with multiple myeloma after high-dose treatment with stem cell support." in: Haematologica, Vol. 94, Issue 9, pp. 1274-81, (2009) (PubMed).

Nissen, Vogel, Nexø: "Association of a single nucleotide polymorphic variation in the human chromosome 19q13.3 with drug responses in the NCI60 cell lines." in: Anti-cancer drugs, Vol. 20, Issue 3, pp. 174-8, (2009) (PubMed).

Hosgood, Zhang, Shen, Berndt, Vermeulen, Li, Yin, Yeager, Yuenger, Rothman, Chanock, Smith, Lan: "Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity." in: Occupational and environmental medicine, Vol. 66, Issue 12, pp. 848-53, (2009) (PubMed).

Target Details for CD3EAP

Target: CD3EAP (CD3e Molecule, epsilon Associated Protein (CD3EAP))

Alternative Name: CD3EAP

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation. Isoform 2 has been described as a component of preformed T-cell receptor (TCR) complex.

Molecular Weight: 54986

NCBI Accession: NP_036231

UniProt: O15446