Nucleostemin antibody (C-Term)

Catalog No. ABIN1881380

The Rabbit Polyclonal anti-Nucleostemin antibody has been validated for WB. It is suitable to detect Nucleostemin in samples from Mouse. There are 5+ publications available.

Quick Overview for Nucleostemin antibody (C-Term) (ABIN1881380)

Target: Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nucleostemin antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40720

Product Details anti-Nucleostemin Antibody

Binding Specificity: AA 442-471, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Gnl3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-471 amino acids from the C-terminal region of mouse Gnl3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Nucleostemin antibody (ABIN1881380)

Hirai, Romanova, Kellner, Verma, Rayner, Asakura, Kikyo: "Post-mitotic role of nucleostemin as a promoter of skeletal muscle cell differentiation." in: Biochemical and biophysical research communications, Vol. 391, Issue 1, pp. 299-304, (2010) (PubMed).

Tamase, Muraguchi, Naka, Tanaka, Kinoshita, Hoshii, Ohmura, Shugo, Ooshio, Nakada, Sawamoto, Onodera, Matsumoto, Oshima, Asano, Saya, Okano, Suda, Hamada, Hirao: "Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 40, pp. 17163-8, (2009) (PubMed).

Nomura, Maruyama, Katano, Kato, Zhang, Masui, Mizuno, Okazaki, Nishimoto, Okuda: "Differential requirement for nucleostemin in embryonic stem cell and neural stem cell viability." in: Stem cells (Dayton, Ohio), Vol. 27, Issue 5, pp. 1066-76, (2009) (PubMed).

Ohmura, Naka, Hoshii, Muraguchi, Shugo, Tamase, Uema, Ooshio, Arai, Takubo, Nagamatsu, Hamaguchi, Takagi, Ishihara, Sakurada, Miyaji, Suda, Hirao: "Identification of stem cells during prepubertal spermatogenesis via monitoring of nucleostemin promoter activity." in: Stem cells (Dayton, Ohio), Vol. 26, Issue 12, pp. 3237-46, (2008) (PubMed).

Siddiqi, Gude, Hosoda, Muraski, Rubio, Emmanuel, Fransioli, Vitale, Parolin, DAmario, Schaefer, Kajstura, Leri, Anversa, Sussman: "Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge." in: Circulation research, Vol. 103, Issue 1, pp. 89-97, (2008) (PubMed).

Target Details for Nucleostemin

Target: Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

Alternative Name: Gnl3

Background: Gnl3 may be required to maintain the proliferative capacity of stem cells (By similarity).

Molecular Weight: 60786

NCBI Accession: NP_705775

UniProt: Q8CI11