GSTT2 antibody (AA 113-141)

Catalog No. ABIN1881394

This Rabbit Polyclonal antibody specifically detects GSTT2 in WB and IHC (p). It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for GSTT2 antibody (AA 113-141) (ABIN1881394)

Target: GSTT2 (Glutathione S-Transferase theta 2 (GSTT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB41723

Product Details anti-GSTT2 Antibody

Binding Specificity: AA 113-141

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GSTT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-141 amino acids from the Central region of human GSTT2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:100. IHC-P: 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-GSTT2 antibody (ABIN1881394)

Canova, Richiardi, Merletti, Pentenero, Gervasio, Tanturri, Garzino-Demo, Pecorari, Talamini, Barzan, Sulfaro, Franchini, Muzzolini, Bordin, Pugliese, Macrì, Simonato: "Alcohol, tobacco and genetic susceptibility in relation to cancers of the upper aerodigestive tract in northern Italy." in: Tumori, Vol. 96, Issue 1, pp. 1-10, (2010) (PubMed).

Wang, Chanock, Tang, Li, Edwards, Jedrychowski, Perera: "Effect of gene-environment Interactions on mental development in African American, Dominican, and Caucasian mothers and newborns." in: Annals of human genetics, Vol. 74, Issue 1, pp. 46-56, (2010) (PubMed).

Moyer, Sun, Batzler, Li, Schaid, Yang, Weinshilboum: "Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 3, pp. 811-21, (2010) (PubMed).

Target Details for GSTT2

Target: GSTT2 (Glutathione S-Transferase theta 2 (GSTT2))

Alternative Name: GSTT2

Background: Glutathione S-transferase (GSTs) theta 2 (GSTT2) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: Alpha, Mu, Pi, Theta, and Zeta. The theta class members GSTT1 and GSTT2 share 55 % amino acid sequence identity and both are thought to have an important role in human carcinogenesis. The theta genes have a similar structure, being composed of five exons with identical exon/intron boundaries.

Molecular Weight: 27506

UniProt: P0CG29

Pathways: Myometrial Relaxation and Contraction, Autophagy