HNRNPH1 antibody (N-Term)

Catalog No. ABIN1881424

This Rabbit Polyclonal antibody specifically detects HNRNPH1 in WB. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for HNRNPH1 antibody (N-Term) (ABIN1881424)

Target: HNRNPH1 (Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPH1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB42336

Product Details anti-HNRNPH1 Antibody

Binding Specificity: AA 48-77, N-Term

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HNRNPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human HNRNPH1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-HNRNPH1 antibody (ABIN1881424)

Van Dusen, Yee, McNally, McNally: "A glycine-rich domain of hnRNP H/F promotes nucleocytoplasmic shuttling and nuclear import through an interaction with transportin 1." in: Molecular and cellular biology, Vol. 30, Issue 10, pp. 2552-62, (2010) (PubMed).

Rauch, ONeill, Mack, Matthias, Munz, Kolch, Gires: "Heterogeneous nuclear ribonucleoprotein H blocks MST2-mediated apoptosis in cancer cells by regulating A-Raf transcription." in: Cancer research, Vol. 70, Issue 4, pp. 1679-88, (2010) (PubMed).

Fisette, Toutant, Dugré-Brisson, Desgroseillers, Chabot: "hnRNP A1 and hnRNP H can collaborate to modulate 5' splice site selection." in: RNA (New York, N.Y.), Vol. 16, Issue 1, pp. 228-38, (2009) (PubMed).

Target Details for HNRNPH1

Target: HNRNPH1 (Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1))

Alternative Name: HNRNPH1

Background: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPF. This gene is thought to be potentially involved in hereditary lymphedema type I phenotype. [provided by RefSeq].

Molecular Weight: 49229

NCBI Accession: NP_001244222, NP_005511

UniProt: P31943