HPSE antibody (AA 26-54)
Quick Overview for HPSE antibody (AA 26-54) (ABIN1881437)
Target
See all HPSE AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 26-54
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This HPSE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the Central region of human HPSE.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- HPSE (Heparanase (HPSE))
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Alternative Name
- HPSE
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Background
- Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Due to its contribution to metastasis and angiogenesis, it is considered to be a potential target for anti-cancer therapies.
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Molecular Weight
- 10338
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UniProt
- E9PFG6
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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