CCKAR antibody (C-Term)

Catalog No. ABIN1881514

This Rabbit Polyclonal antibody specifically detects CCKAR in WB. It exhibits reactivity toward Mouse and has been mentioned in 2+ publications.

Quick Overview for CCKAR antibody (C-Term) (ABIN1881514)

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCKAR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCKAR Antibody

Binding Specificity: AA 325-356, C-Term

Predicted Reactivity: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Cckar antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-356 amino acids from the C-terminal region of mouse Cckar.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-CCKAR antibody (ABIN1881514)

Lacourse, Lay, Swanberg, Jenkins, Samuelson: "Molecular structure of the mouse CCK-A receptor gene." in: Biochemical and biophysical research communications, Vol. 236, Issue 3, pp. 630-5, (1997) (PubMed).

Takata, Takiguchi, Kataoka, Funakoshi, Miyasaka, Kono: "Mouse cholecystokinin type-A receptor gene and its structural analysis." in: Gene, Vol. 187, Issue 2, pp. 267-71, (1997) (PubMed).

Target Details for CCKAR

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Alternative Name: Cckar

Background: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).

Molecular Weight: 48437

NCBI Accession: NP_033957

UniProt: O08786

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Feeding Behaviour