PNPLA2 antibody (N-Term)

Catalog No. ABIN1881664

This Rabbit Polyclonal antibody specifically detects PNPLA2 in WB. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for PNPLA2 antibody (N-Term) (ABIN1881664)

Target: PNPLA2 (Patatin-Like phospholipase Domain Containing 2 (PNPLA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNPLA2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40409

Product Details anti-PNPLA2 Antibody

Binding Specificity: AA 49-78, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PNPLA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-78 amino acids from the N-terminal region of human PNPLA2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-PNPLA2 antibody (ABIN1881664)

Kamikubo, Kai, Tsuji-Naito, Akagawa: "β-Caryophyllene attenuates palmitate-induced lipid accumulation through AMPK signaling by activating CB2 receptor in human HepG2 hepatocytes." in: Molecular nutrition & food research, Vol. 60, Issue 10, pp. 2228-2242, (2017) (PubMed).

Target Details for PNPLA2

Target: PNPLA2 (Patatin-Like phospholipase Domain Containing 2 (PNPLA2))

Alternative Name: PNPLA2

Background: Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.

Molecular Weight: 55316

NCBI Accession: NP_065109

UniProt: Q96AD5