HSP90AB1 antibody (N-Term)

Catalog No. ABIN1882093

This Rabbit Polyclonal antibody specifically detects HSP90AB1 in WB and IHC (p). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for HSP90AB1 antibody (N-Term) (ABIN1882093)

Target: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSP90AB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB17751

Product Details anti-HSP90AB1 Antibody

Binding Specificity: AA 42-74, N-Term

Predicted Reactivity: B, Hs, Pr, M, Rb, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This HSPCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-74 amino acids from the N-terminal region of human HSPCB.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-HSP90AB1 antibody (ABIN1882093)

Chadli, Felts, Wang, Sullivan, Botuyan, Fauq, Ramirez-Alvarado, Mer: "Celastrol inhibits Hsp90 chaperoning of steroid receptors by inducing fibrillization of the Co-chaperone p23." in: The Journal of biological chemistry, Vol. 285, Issue 6, pp. 4224-31, (2010) (PubMed).

Target Details for HSP90AB1

Target: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Alternative Name: HSPCB

Background: HSPCB proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSPCB proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress.

Molecular Weight: 83264

NCBI Accession: NP_001258898, NP_001258899, NP_001258900, NP_031381

UniProt: P08238

Pathways: Regulation of Cell Size