POU2AF1 antibody

Catalog No. ABIN1882276

This Mouse Monoclonal antibody specifically detects POU2AF1 in WB. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for POU2AF1 antibody (ABIN1882276)

Target: POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This POU2AF1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 1170CT1-1-1

Product Details anti-POU2AF1 Antibody

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged POU2AF1 protein was used to produced this monoclonal antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:4000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-POU2AF1 antibody (ABIN1882276)

Galiègue-Zouitina, Quief, Hildebrand, Denis, Lecocq, Collyn-dHooghe, Bastard, Yuille, Dyer, Kerckaert: "Fusion of the LAZ3/BCL6 and BOB1/OBF1 genes by t(3; 11) (q27; q23) chromosomal translocation." in: Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie, Vol. 318, Issue 11, pp. 1125-31, (1996) (PubMed).

Luo, Roeder: "Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B." in: Molecular and cellular biology, Vol. 15, Issue 8, pp. 4115-24, (1995) (PubMed).

Target Details for POU2AF1

Target: POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

Alternative Name: POU2AF1

Background: Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.

Molecular Weight: 27436

NCBI Accession: NP_006226

UniProt: Q16633