APRT
Reactivity: Human, Rat, Dog
WB, IHC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.100-1.500 Immunofluorescence: 1.100-1.200
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
APRT
(Adenine Phosphoribosyltransferase (APRT))
Alternative Name
APRT
Background
Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family.A conserved feature of this gene is the distribution of CpG dinucleotides.This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP).It also produces adenine as a by-product of the polyamine biosynthesis pathway.A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]