Desmoglein 2 antibody (AA 1-176)

Catalog No. ABIN1885699

This Rabbit Polyclonal antibody specifically detects Desmoglein 2 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Desmoglein 2 antibody (AA 1-176) (ABIN1885699)

Target: Desmoglein 2 (DSG2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmoglein 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Desmoglein 2 Antibody

Binding Specificity: AA 1-176

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 176 of Desmoglein-2

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Desmoglein 2

Target: Desmoglein 2 (DSG2)

Alternative Name: Desmoglein-2

Background: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types.This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells.Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily.These desmoglein gene family members are located in a cluster on chromosome 18.This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.[provided by RefSeq]

Molecular Weight: 122 kDa

Gene ID: 1829

NCBI Accession: NP_001934, NM_001943

Pathways: Cell-Cell Junction Organization