SAP130 antibody (AA 1154-1217)

Catalog No. ABIN1885970

The Rabbit Polyclonal anti-SAP130 antibody has been validated for WB and IHC. It is suitable to detect SAP130 in samples from Human.

Quick Overview for SAP130 antibody (AA 1154-1217) (ABIN1885970)

Target: SAP130 (Sin3A-Associated Protein, 130kDa (SAP130))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAP130 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SAP130 Antibody

Binding Specificity: AA 1154-1217

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 1154 and 1217 of SAP130

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 1 x PBS, 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for SAP130

Target: SAP130 (Sin3A-Associated Protein, 130kDa (SAP130))

Alternative Name: SAP130

Background: This gene encodes subunit 3 of the splicing factor 3b protein complex.Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP).The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA.Splicing factor 3b is also a component of the minor U12-type spliceosome.Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex).These complexes may function in chromatin modification, transcription, splicing, and DNA repair.[provided by RefSeq]

Molecular Weight: 136 kDa

Gene ID: 23450

NCBI Accession: NP_036558, NM_012426