CD70 antibody (AA 129-193)

Catalog No. ABIN1886003

The Rabbit Polyclonal anti-CD70 antibody has been validated for WB. It is suitable to detect CD70 in samples from Human.

Quick Overview for CD70 antibody (AA 129-193) (ABIN1886003)

Target: CD70 (CD70 Molecule (CD70))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD70 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD70 Antibody

Binding Specificity: AA 129-193

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 129 and 193 of CD27L (CD70)

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: CD27L(CD27L(CD70))

Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.This cytokine is a ligand for TNFRSF27/CD27.It is a surface antigen on activated, but not on resting, T and B lymphocytes.It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation.This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.[provided by RefSeq]

Molecular Weight: 21 kDa

Gene ID: 970

NCBI Accession: NM_001252, NP_001243

Pathways: Cancer Immune Checkpoints