MVP
Reactivity: Human
FACS, IF
Host: Mouse
Monoclonal
1014
unconjugated
Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.100-1.500 Immunofluorescence: 1.100-1.200
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
MVP
(Major Vault Protein (MVP))
Alternative Name
LRP(MVP)
Background
This gene encodes the major vault protein which is a lung resistance-related protein.Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport.This protein mediates drug resistance, perhaps via a transport process.It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells.The protein overexpression is a potentially useful marker of clinical drug resistance.This gene produces two transcripts by using two alternative exon 2 sequences, however, the open reading frames are the same in both transcripts.[provided by RefSeq]