PUF60 antibody (AA 346-533)

Catalog No. ABIN1886388

This anti-PUF60 antibody is a Rabbit Polyclonal antibody detecting PUF60 in WB, IHC and IF. Suitable for Human.

Quick Overview for PUF60 antibody (AA 346-533) (ABIN1886388)

Target: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUF60 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PUF60 Antibody

Binding Specificity: AA 346-533

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 346 and 533 of Human PUF60

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for PUF60

Target: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Alternative Name: PUF60

Background: The protein encoded by this gene is a Ro RNP-binding protein.It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs.This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein.It can repress a c-myc reporter via the FUSE.It is also known to target transcription factor IIH and inhibit activated transcription.This gene is implicated in the xeroderma pigmentosum disorder.There are two alternatively spliced transcript variants of this gene encoding different isoforms.There seems to be evidence of multiple polyadenylation sites for this gene.[provided by RefSeq]
Synonyms: FIR, PUF60, RoBPI

Molecular Weight: 58 kDa

Gene ID: 22827

NCBI Accession: NP_055096, NM_014281