Ubiquilin 1 antibody (AA 64-315)

Catalog No. ABIN1886597

The Rabbit Polyclonal anti-Ubiquilin 1 antibody has been validated for WB and IF. It is suitable to detect Ubiquilin 1 in samples from Human.

Quick Overview for Ubiquilin 1 antibody (AA 64-315) (ABIN1886597)

Target: Ubiquilin 1 (UBQLN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ubiquilin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Ubiquilin 1 Antibody

Binding Specificity: AA 64-315

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 64 and 315 of Ubiquilin-1

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Ubiquilin 1

Target: Ubiquilin 1 (UBQLN1)

Alternative Name: Ubiquilin-1

Background: This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog.Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain.They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation.This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease.Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

Molecular Weight: 63 kDa

Gene ID: 29979

NCBI Accession: NP_038466, NM_013438