ZKSCAN1 antibody (C-Term)

Catalog No. ABIN1887312

This anti-ZKSCAN1 antibody is a Rabbit Polyclonal antibody detecting ZKSCAN1 in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for ZKSCAN1 antibody (C-Term) (ABIN1887312)

Target: ZKSCAN1 (Zinc Finger with KRAB and SCAN Domains 1 (ZKSCAN1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZKSCAN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ZKSCAN1 Antibody

Binding Specificity: C-Term

Cross-Reactivity (Details): ZNF346 antibody is predicted to not cross-react with other ZNF family members. Three isoforms of ZNF346 are known to exist, this antibody will recognize the two longest isoforms

Purification: Affinity chromatography purified via peptide column

Immunogen: 20 amino acid peptide near the carboxy terminus of human ZNF346.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for ZKSCAN1

Target: ZKSCAN1 (Zinc Finger with KRAB and SCAN Domains 1 (ZKSCAN1))

Background: ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers.ZNF346 contains four CH-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences.ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus.ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism.ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.
Synonyms: Zinc finger protein 346, Just another zinc finger protein, JAZ

NCBI Accession: NP_036411