WNV E antibody (C-Term)

Catalog No. ABIN1887443

The Rabbit Polyclonal anti-WNV E antibody has been validated for ELISA. It is suitable to detect WNV E in samples from West Nile Virus (WNV).

Quick Overview for WNV E antibody (C-Term) (ABIN1887443)

Target: WNV E (West Nile Virus Envelope (WNV E))

Reactivity: West Nile Virus (WNV)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNV E antibody is un-conjugated

Application: ELISA

Product Details anti-WNV E Antibody

Binding Specificity: C-Term

Purification: Affinity chromatography purified via peptide column

Immunogen: Synthetic peptide corresponding to 14 amino acids at the C-terminus of the West Nile Virus envelope protein.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for WNV E

Target: WNV E (West Nile Virus Envelope (WNV E))

Alternative Name: West Nile Virus Envelope

Target Type: Viral Protein

Background: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St.Louis encephalitis virus, yellow fever virus, and Dengue virus.WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe.It has rapidly spread across the United States with cases being observed in every continental state.Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins.While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway, the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein.The WNV receptor has recently been identified as alpha v beta 3 integrin.
Synonyms: WNV Env

NCBI Accession: NP_776014