Calcineurin A antibody (AA 264-283)

Catalog No. ABIN190682

This Rabbit Polyclonal antibody specifically detects Calcineurin A in WB and IP. It exhibits reactivity toward Human.

Quick Overview for Calcineurin A antibody (AA 264-283) (ABIN190682)

Target: Calcineurin A (CAN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calcineurin A antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Calcineurin A Antibody

Binding Specificity: AA 264-283

Purpose: Anti-Calcineurin A (Catalytic) Rabbit Polyclonal Antibody

Cross-Reactivity: Cow, Dog, Hamster, Human, Mouse, Rabbit, Rat

Purification: Affinity - Purified

Immunogen: Synthetic peptide corresponding to aa 264-283 of human Calcineurin A conjugated to KLH. This sequence is identical in rat and mouse calcineurin A.

Application Details

Application Notes: Immunoblotting: Use at 1-5 μg/mL. A band of ~61 kDa is detected.
These are recommended concentrations.
Endusers should determine optimal concentrations for their application.

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Concentration: Lot specific

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: This antibody is stable for at least one (1) year at -20°C.

Target Details for Calcineurin A

Target: Calcineurin A (CAN)

Alternative Name: Calcineurin A

Background: Serine/threonine-protein phosphatase 2B catalytic subunit α isoform,Calcineurin is a Ca+2/calmodulin-dependent serine/threonine protein phosphatase. The active enzyme is a heterodimer consisting of a catalytic A subunit and a myristylated regulatory B subunit that binds calcium. It controls the translocation of nuclear factors from the cytosol into the nucleus of activated T cells. Calcineurin is a target of immunosuppressive drugs such as cyclosporin A and FK506.,EC 3.1.3.16, CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit α isoform

Gene ID: 5530

NCBI Accession: NP_000935