MSTN antibody

Catalog No. ABIN191941

This anti-MSTN antibody is a Mouse Monoclonal antibody detecting MSTN in EIA. Suitable for Human.

Quick Overview for MSTN antibody (ABIN191941)

Target: MSTN (Myostatin (MSTN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MSTN antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: 4D

Product Details anti-MSTN Antibody

Specificity: This antibody detects Myostatin prodomain.

Characteristics: Synonyms: MSTN, GDF8, GDF-8, Growth differentiation factor 8

Purification: Protein G Chromatography

Immunogen: Recombinant Myostatin

Isotype: IgG2b

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in aqua bidest to 1 mg/mL.

Buffer: 50 mM TRIS, pH 7.4

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing.
Shelf life: One year from despatch.

Expiry Date: 12 months

Target Details for MSTN

Target: MSTN (Myostatin (MSTN))

Alternative Name: Myostatin

Background: Myostatin (GDF8) is expressed uniquely in human skeletal muscle as a 12 kDa mature glycoprotein consisting of 113 amino acid residues and secreted into plasma. Myostatin is a member of the transforming growth factor ß superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass. Studies have shown that myostatin could play an important role in cardiac development and physiology. In serum, myostatin circulates as part of a latent complex containing myostatin propeptide and/or follistatin-related gene. The myostatin propeptide is known to bind and inhibit myostatin in vitro. This interaction is relevant in vivo, with a majority (>70 % ) of myostatin in serum bound to its propeptide. The myostatin propeptide is negative regulator of myostatin in vivo.Synonyms: GDF-8, GDF8, Growth differentiation factor 8, MSTN

Gene ID: 2660

UniProt: O14793