TCL1A antibody (AA 32-66)

Catalog No. ABIN1944776

The Rabbit Polyclonal anti-TCL1A antibody has been validated for WB and FACS. It is suitable to detect TCL1A in samples from Human. There are 3+ publications available.

Quick Overview for TCL1A antibody (AA 32-66) (ABIN1944776)

Target: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCL1A antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB48087

Product Details anti-TCL1A Antibody

Binding Specificity: AA 32-66

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TCL1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-66 amino acids from the Central region of human TCL1A.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-TCL1A antibody (ABIN1944776)

Laine, Künstle, Obata, Sha, Noguchi: "The protooncogene TCL1 is an Akt kinase coactivator." in: Molecular cell, Vol. 6, Issue 2, pp. 395-407, (2000) (PubMed).

Virgilio, Narducci, Isobe, Billips, Cooper, Croce, Russo: "Identification of the TCL1 gene involved in T-cell malignancies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 26, pp. 12530-4, (1995) (PubMed).

Fu, Virgilio, Narducci, Facchiano, Russo, Croce: "Characterization and localization of the TCL-1 oncogene product." in: Cancer research, Vol. 54, Issue 24, pp. 6297-301, (1995) (PubMed).

Target Details for TCL1A

Target: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Alternative Name: TCL1A

Background: Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.

Molecular Weight: 13460

Gene ID: 8115

UniProt: P56279

Pathways: Stem Cell Maintenance