GJB1 antibody (AA 95-125)

Catalog No. ABIN199013

The Mouse Monoclonal anti-GJB1 antibody has been validated for WB and IHC. It is suitable to detect GJB1 in samples from Human, Rat and Mouse.

Quick Overview for GJB1 antibody (AA 95-125) (ABIN199013)

Target: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This GJB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GJB1 Antibody

Binding Specificity: AA 95-125

Specificity: Recognizes rat Connexin-32. Species cross-reactivity: human and mouse.

Purification: Purified

Immunogen: Directed against an epitope located between residues 95-125 in the central cytoplasmic loop of rat Cx32.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, WB

Usage: Suitable for use in Immunohistochemistry (lightly formaldehyde fixed tissues) and Western Blot. Western blot: Detects a 27kD Connexin 32 polypeptide in blots of rat hepatocyte gap junctions and an additional 47kD band corresponding to aggregates.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.1 % sodium azide, 40 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for GJB1

Target: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Alternative Name: GJB1 / CX32 / Connexin 32

Background: Name/Gene ID: GJB1
Subfamily: Connexin
Family: Ion Channel

Synonyms: GJB1, Connexin 32, CMTX1, Connexin-32, CX32, Gap junction beta-1 protein, Gap junction protein beta-1, CMTX

Gene ID: 2705

UniProt: P08034

Pathways: Cell-Cell Junction Organization