Haptoglobin antibody (FITC)

Catalog No. ABIN1992508

This Rabbit Polyclonal antibody specifically detects Haptoglobin in WB, IHC and ELISA. It exhibits reactivity toward Rat.

Quick Overview for Haptoglobin antibody (FITC) (ABIN1992508)

Target: Haptoglobin (HP)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Haptoglobin antibody is conjugated to FITC

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Haptoglobin Antibody (FITC)

Purification: Caprylic Acid Ammonium Sulfate Precipitation

Immunogen: Recombinant rat Haptoglobin protein

Isotype: IgG

Application Details

Application Notes: Optimal working concentration should be determinde by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.

Storage: -20 °C/-80 °C

Storage Comment: Upon delivery aliquot and store at -20 °C or -80 °C.

Target Details for Haptoglobin

Target: Haptoglobin (HP)

Alternative Name: Haptoglobin

Background: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway?.Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
Synonyms: Liver regeneration-related protein LRRG173, Zonulin,Hp,Ba1-647

UniProt: P06866

Pathways: Transition Metal Ion Homeostasis