Histone H2B Type 1-C/E/F/G/I (LOC100407767) antibody (Biotin)

Catalog No. ABIN1992617

Product Details

Target:

Histone H2B Type 1-C/E/F/G/I (LOC100407767)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: ELISA, Western Blotting (WB)

Purification: Caprylic Acid Ammonium Sulfate Precipitation

Immunogen: Recombinant human Histone H2B type 1-C/E/F/G/I protein

Isotype: IgG

Application Details

Application Notes: Optimal working concentration should be determinde by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.

Storage: -20 °C/-80 °C

Storage Comment: Upon delivery aliquot and store at -20 °C or -80 °C.

Target Details

Target:

Histone H2B Type 1-C/E/F/G/I (LOC100407767)

Alternative Name: Histone H2B type 1-C/E/F/G/I (LOC100407767 Antibody Abstract)

Synonyms: H2B.1, H2B/l, H2BFL, dJ221C16.3, histone cluster 1 H2B family member c, HIST1H2BC

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.

UniProt: P62807