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Histone H2B Products

(Histone H2B)
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Jul 2008].

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Featured Histone H2B Categories

Histone H2B Antibodies

High quality antibodies with extensive validation data.

Histone H2B ELISA Kits

Reliable ELISA kits for a wide range of species.

Histone H2B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Histone H2B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (8)
Cat. No. ABIN7258526
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN7258524
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN7258518
Quantity 200 μL
Datasheet Datasheet

Recommended Histone H2B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967442
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956583
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1115439
Quantity 96 tests
Datasheet Datasheet

Recommended Histone H2B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306675
Quantity 10 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406707
Quantity 100 μg
Datasheet Datasheet
Reactivity CHO cells
Source Insect Cells
Validations
Cat. No. ABIN7126086
Quantity 0.5 mg
Datasheet Datasheet

Latest Publications for our Histone H2B products

Munemasa: "Histone H2B induces retinal ganglion cell death through toll-like receptor 4 in the vitreous of acute primary angle closure patients." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 100, Issue 8, pp. 1080-1089, (2020) (PubMed).

Brahma, Henikoff: "RSC-Associated Subnucleosomes Define MNase-Sensitive Promoters in Yeast." in: Molecular cell, Vol. 73, Issue 2, pp. 238-249.e3, (2019) (PubMed).

Lin, Chang, Wu, Lin, Chang, Yang, Huang, Hsu, Chang, Chen: "Proteome Profiling of Urinary Exosomes Identifies Alpha 1-Antitrypsin and H2B1K as Diagnostic and Prognostic Biomarkers for Urothelial Carcinoma." in: Scientific reports, Vol. 6, pp. 34446, (2016) (PubMed).

Vlaming, Molenaar, van Welsem, Poramba-Liyanage, Smith, Velds, Hoekman, Korthout, Hendriks, Altelaar, van Leeuwen: "Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1." in: eLife, Vol. 5, (2016) (PubMed).

Chen, DArcy, Radebaugh, Krzizike, Giebler, Huang, Nyborg, Luger, Stargell: "Histone Chaperone Nap1 Is a Major Regulator of Histone H2A-H2B Dynamics at the Inducible GAL Locus." in: Molecular and cellular biology, Vol. 36, Issue 8, pp. 1287-96, (2016) (PubMed).

Materne, Vázquez, Sánchez, Yague-Sanz, Anandhakumar, Migeot, Antequera, Hermand: "Histone H2B ubiquitylation represses gametogenesis by opposing RSC-dependent chromatin remodeling at the ste11 master regulator locus." in: eLife, Vol. 5, (2016) (PubMed).

Stulemeijer, De Vos, van Harten, Joshi, Blomberg, van Welsem, Terweij, Vlaming, de Graaf, Altelaar, Bakker, van Leeuwen: "Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties." in: Scientific reports, Vol. 5, pp. 9824, (2015) (PubMed).

Zheng, Crickard, Srikanth, Reese: "A highly conserved region within H2B is important for FACT to act on nucleosomes." in: Molecular and cellular biology, Vol. 34, Issue 3, pp. 303-14, (2014) (PubMed).

Bonizec, Hérissant, Pokrzywa, Geng, Wenzel, Howard, Rodriguez, Krause, Tansey, Hoppe, Dargemont: "The ubiquitin-selective chaperone Cdc48/p97 associates with Ubx3 to modulate monoubiquitylation of histone H2B." in: Nucleic acids research, Vol. 42, Issue 17, pp. 10975-86, (2014) (PubMed).

Mbogning, Nagy, Pagé, Schwer, Shuman, Fisher, Tanny: "The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pathways regulating transcription elongation in fission yeast." in: PLoS genetics, Vol. 9, Issue 12, pp. e1004029, (2014) (PubMed).

Synonyms and alternative names related to Histone H2B

histone cluster 1 H2B family member k (Hist1h2bk), histone H2B (H2B), histone B2 (HTB2), histone H2B (THAPSDRAFT_27352), histone H2B (THAPSDRAFT_37309), histone H2B (THAPS_6947), histone H2B (THAPSDRAFT_34210), histone H2B (LOC426037), histone H2B.3 (LOC107802329), H2B, H2B1, HIS2B, Hist1h2bc, histone B2, HISTONE H2B, MRN17.11, MRN17_11

Protein level used designations for Histone H2B

  • histone H2B
  • histone cluster 1, H2bc
  • histone H2B (partial) (3AA)
  • Histone H2B
  • histone H2B.3
  • histone H2B1
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