Desmoglein 1 antibody (Intracellular)

Catalog No. ABIN200783

The Mouse Monoclonal anti-Desmoglein 1 antibody has been validated for WB, IHC, IF, IP and IHC (fro). It is suitable to detect Desmoglein 1 in samples from Human.

Quick Overview for Desmoglein 1 antibody (Intracellular) (ABIN200783)

Target: Desmoglein 1 (DSG1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Desmoglein 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Desmoglein 1 Antibody

Binding Specificity: Intracellular

Specificity: Recognizes the ~165kD human desmoglein-1 protein. This antibody does not cross-react with desmoglein-2 or desmoglein-3 protein.

Purification: Protein A purified

Immunogen: Human desmoglein-1 intracellular domain.

Type of Immunogen: Purified protein

Isotype: IgG1

Application Details

Application Notes: Approved: IF, IHC, IHC-Fr, IP, WB (1 - 3 μg/mL)

Usage: Suitable for use in Western Blot, Immunoprecipitation, Immunofluorescence and Immunohistochemistry. Immunoprecipitation: 5-10 μg. Western Blot: 1-3 μg/mL. Immunohistochemistry (Frozen): 20-50 μg/mL. Positive control: Differentiated keratinocytes and Desmoglein-1 transfected cells.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for Desmoglein 1

Target: Desmoglein 1 (DSG1)

Alternative Name: DSG1 / Desmoglein 1

Background: Name/Gene ID: DSG1
Family: Cadherin

Synonyms: DSG1, CDHF4, Cadherin family member 4, Desmoglein 1, DG1, Desmoglein-1, Desmosomal glycoprotein 1, SPPK1, DGI, DSG, Pemphigus foliaceus antigen, PPKS1

Gene ID: 1828

UniProt: Q02413

Pathways: Cell-Cell Junction Organization