Transferrin antibody (N-Term)
Quick Overview for Transferrin antibody (N-Term) (ABIN206901)
Target
See all Transferrin (TF) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- N-Term
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Specificity
- Recognizes an epitope located in the N-terminal domain of human serum transferrin, a 77 kD single polypeptide chain glycoprotein (member of the iron binding family of proteins). It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+.
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No Cross-Reactivity
- Cow (Bovine), Sheep (Ovine), Dog (Canine), Horse (Equine)
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Purification
- Ion exchange chromatography
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Immunogen
- Purified porcine transferrin.
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Isotype
- IgG1
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Application Notes
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Approved: Block, ELISA, Func, ICC, Neut, RIA, WB
Usage: Western Blotting: Application note - non-reducing conditions. Immunohistochemistry (paraffin sections): Recommended dilution - 10 μg/mL. Positive tissue - placenta. Functional Application: The antibody HTF-14 blocks binding of transferrin to the receptor. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Not recommended for: IHC-P -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 15 mM sodium azide, pH 7.4
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Preservative
- Azide free
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Handling Advice
- avoid freeze thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- Transferrin (TF)
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Alternative Name
- TF / Transferrin
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Background
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Name/Gene ID: TF
Synonyms: TF, PRO1557, Serotransferrin, Siderophilin, TFQTL1, Beta-1 metal-binding globulin, Transferrin, PRO2086 -
Gene ID
- 7018
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UniProt
- P02787
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Pathways
- Transition Metal Ion Homeostasis
Target
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