GRAP2 antibody (AA 174-188)

Catalog No. ABIN210889

This Rabbit Polyclonal antibody specifically detects GRAP2 in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for GRAP2 antibody (AA 174-188) (ABIN210889)

Target: GRAP2 (GRB2-Related Adaptor Protein 2 (GRAP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRAP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-GRAP2 Antibody

Binding Specificity: AA 174-188

Specificity: Recognizes human GADS, Mr 40kD. Species cross-reactivity: Mouse.

Predicted Reactivity: Percent identity by BLAST analysis: Mouse (100%) Human, Gorilla, Gibbon, Monkey, Elephant, Horse, Rabbit (93%) Rat, Panda, Bovine, Pig (87%) Dog, Bat, Opossum (80%).

Purification: Protein A purified

Immunogen: KLH-conjugated, synthetic peptide corresponding to aa174-188 of mouse GADS (GEEIRPSVNRKLSDH). The immunizing sequence shares 14/15 identity with human GADS. Percent identity by BLAST analysis: Mouse (100%), Human, Gorilla, Gibbon, Monkey, Elephant, Horse, Rabbit (93%), Rat, Panda, Bovine, Pig (87%), Dog, Bat, Opossum (80%).

Type of Immunogen: Synthetic peptide - KLH conjugated

Isotype: IgG

Application Details

Application Notes: Approved: IP, WB

Usage: Suitable for use in Western Blot and Immunoprecipitation. Western Blot Analysis: 0.5-2 μg/mL of this lot detected GADS from a Jurkat RIPA cell lysate. Immunoprecipitation: This antibody has been reported by an independent laboratory to immunoprecipitate GADS.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.1 M Tris-glycine,  pH 7.4, 0.15 M sodium chloride, 0.05 % sodium azide, 30 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for GRAP2

Target: GRAP2 (GRB2-Related Adaptor Protein 2 (GRAP2))

Alternative Name: GRAP2 / GRID

Background: Name/Gene ID: GRAP2

Synonyms: GRAP2, Adapter protein GRID, GRAP-2, GRB2L, Grf40 adapter protein, GRB2-related adapter protein 2, GRBLG, Grf-40, Grf40, GRB2-related adaptor protein 2, GRID, MONA, Protein GADS, SH3-SH2-SH3 adaptor molecule, SH3-SH2-SH3 adapter Mona, GADS, GRB-2-like protein, GrbX, GRPL, p38

Gene ID: 9402

UniProt: O75791

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway