INPP5D antibody (AA 7-133)

Catalog No. ABIN210962

The Rabbit Polyclonal anti-INPP5D antibody has been validated for WB and IP. It is suitable to detect INPP5D in samples from Human and Mouse.

Quick Overview for INPP5D antibody (AA 7-133) (ABIN210962)

Target: INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INPP5D antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-INPP5D Antibody

Binding Specificity: AA 7-133

Specificity: Recognizes SHIP, 145kD and/or 135kD as well as C-terminal truncated forms at 125kD and 110kD in some cell types. Species cross-reactivity: human and mouse.

Purification: Protein A purified

Immunogen: Fusion protein corresponding to aa7-133 of murine SHIP SH2 domain.

Type of Immunogen: Fusion protein

Isotype: IgG

Application Details

Application Notes: Approved: IP, WB

Usage: Suitable for use in Western Blot and Immunoprecipitation. Proteins were visualized using a goat anti-rabbit IgG labeled with HRP and a chemiluminescence detection system. Immunoprecipitation: 2 μg Reported to immunoprecipitate SHIP from Ramos cells (human B cell line). The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.07 M Tris,  pH 7.4, 0.105 M sodium chloride. No stabilizing proteins added. No preservative added.

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for INPP5D

Target: INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))

Alternative Name: INPP5D / SHIP1 / SHIP

Background: Name/Gene ID: INPP5D
Family: Inositol Phosphatase

Synonyms: INPP5D, p150Ship, SHIP, SHIP1, SHIP-1, Hp51CN, SIP-145

Gene ID: 3635

UniProt: Q92835

Pathways: TCR Signaling, BCR Signaling, Warburg Effect