Osteocalcin antibody (AA 1-19)
Quick Overview for Osteocalcin antibody (AA 1-19) (ABIN211484)
Target
See all Osteocalcin (BGLAP) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-19
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Specificity
- Recognizes intact human osteocalcin in a 2 site assay and reacts with osteocalcin fragments corresponding to amino acids 1-19, 7-19 and 15-31 of the native molecule. It does not recognize fragments representing amino acids 20-42 or intact bovine osteocalcin. Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kD), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Pageta€™s disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.
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No Cross-Reactivity
- Mouse (Murine), Cow (Bovine), Rat (Rattus)
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Purification
- Protein A purified
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Immunogen
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Recombinant human osteocalcin GST fusion protein.
Type of Immunogen: Recombinant protein -
Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Osteocalcin (BGLAP)
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Alternative Name
- Osteocalcin
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Background
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Name/Gene ID: BGLAP
Synonyms: BGLAP, Bone Gla protein, BGP, OC, Osteocalcin -
Gene ID
- 632
Target
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