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Osteocalcin antibody (AA 1-19)

The Mouse Monoclonal anti-Osteocalcin antibody has been validated for ELISA. It is suitable to detect Osteocalcin in samples from Human.
Catalog No. ABIN211484

Quick Overview for Osteocalcin antibody (AA 1-19) (ABIN211484)

Target

See all Osteocalcin (BGLAP) Antibodies
Osteocalcin (BGLAP)

Reactivity

  • 94
  • 30
  • 19
  • 18
  • 18
  • 12
  • 9
  • 9
  • 8
  • 4
  • 4
  • 1
  • 1
  • 1
Human

Host

  • 79
  • 43
  • 2
  • 2
  • 1
Mouse

Clonality

  • 83
  • 44
Monoclonal

Conjugate

  • 84
  • 11
  • 11
  • 7
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Osteocalcin antibody is un-conjugated

Application

  • 86
  • 66
  • 62
  • 26
  • 19
  • 9
  • 8
  • 8
  • 7
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
ELISA
  • Binding Specificity

    • 10
    • 8
    • 8
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-19

    Specificity

    Recognizes intact human osteocalcin in a 2 site assay and reacts with osteocalcin fragments corresponding to amino acids 1-19, 7-19 and 15-31 of the native molecule. It does not recognize fragments representing amino acids 20-42 or intact bovine osteocalcin. Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kD), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Pageta€™s disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.

    No Cross-Reactivity

    Mouse (Murine), Cow (Bovine), Rat (Rattus)

    Purification

    Protein A purified

    Immunogen

    Recombinant human osteocalcin GST fusion protein.

    Type of Immunogen: Recombinant protein

    Isotype

    IgG1
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS, 0.09 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target

    Osteocalcin (BGLAP)

    Alternative Name

    Osteocalcin

    Background

    Name/Gene ID: BGLAP

    Synonyms: BGLAP, Bone Gla protein, BGP, OC, Osteocalcin

    Gene ID

    632
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