Osteocalcin antibody (AA 15-31)

Catalog No. ABIN211486

This Mouse Monoclonal antibody specifically detects Osteocalcin in ELISA. It exhibits reactivity toward Human, Rat, Cow, Rabbit and Pig.

Quick Overview for Osteocalcin antibody (AA 15-31) (ABIN211486)

Target: Osteocalcin (BGLAP)

Reactivity: Human, Rat, Cow, Rabbit, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This Osteocalcin antibody is un-conjugated

Application: ELISA

Product Details anti-Osteocalcin Antibody

Binding Specificity: AA 15-31

Specificity: Recognizes intact human and bovine osteocalcin in a "2 site" assay and reacts with osteocalcin fragments corresponding to amino acids 15-31 and 20-43 of the native molecule. It does not recognize fragments representing amino acids 1-19 or 7-19. Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kD), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Pageta€™s disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.

No Cross-Reactivity: Mouse (Murine)

Purification: Protein A purified

Immunogen: Recombinant human osteocalcin GST fusion protein.

Type of Immunogen: Recombinant protein

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for Osteocalcin

Target: Osteocalcin (BGLAP)

Alternative Name: Osteocalcin

Background: Name/Gene ID: BGLAP

Synonyms: BGLAP, Bone Gla protein, BGP, OC, Osteocalcin

Gene ID: 632

UniProt: P02818