Transferrin antibody (N-Term)

Catalog No. ABIN211539

This anti-Transferrin antibody is a Mouse Monoclonal antibody detecting Transferrin in ELISA, IF and Func. Suitable for Human, Pig and Rabbit.

Quick Overview for Transferrin antibody (N-Term) (ABIN211539)

Target: Transferrin (TF)

Reactivity: Human, Pig, Rabbit

Host: Mouse

Clonality: Monoclonal

Conjugate: This Transferrin antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Functional Studies (Func)

Product Details anti-Transferrin Antibody

Binding Specificity: N-Term

Specificity: Anti transferrin clone HTF-14 is specific for the N-terminal domain of human transferrin and has been shown to block binding of transferrin to the transferrin receptor (CD71). Clone HTF-14 is not able to recognize receptor bound transferrin. Clone HTF-14 recognizes a conformational epitope in a loop of the N lobe of transferrin involving the critical Lys-144 residue, also essential for binding of the N lobe to the transferrin receptor Transferrin is a 77 kD plasma protein synthesized by the liver involved with the transport of iron. Each transferrin molecule has two domains, both with facility to carry 2 ferric ions. The iron/transferrin complex is essential for haemoglobin synthesis and certain types of cell division.

No Cross-Reactivity: Cow (Bovine), Sheep (Ovine), Dog (Canine), Horse (Equine)

Purification: Protein A purified

Immunogen: Purified porcine transferrin ( N-TERMINAL ).

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Transferrin

Target: Transferrin (TF)

Alternative Name: TF / Transferrin

Background: Name/Gene ID: TF

Synonyms: TF, PRO1557, Serotransferrin, Siderophilin, TFQTL1, Beta-1 metal-binding globulin, Transferrin, PRO2086

Gene ID: 7018

UniProt: P02787

Pathways: Transition Metal Ion Homeostasis