CD55 antibody

Catalog No. ABIN7470770

This Mouse Monoclonal antibody specifically detects CD55 in FACS and IP. It exhibits reactivity toward Human.

Quick Overview for CD55 antibody (ABIN7470770)

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD55 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Product Details anti-CD55 Antibody

Specificity: Recognizes the CD55 antigen, a 70kD glycoprotein also known as Decay Accelerating Factor (DAF). Distributed on erythrocytes and other circulating blood cells and also on cells in non-hemopoietic tissue particularly epithelium and endothelium. Found specifically at the fetal-maternal interfaces in placenta. CD55 has reduced expression on individuals with paroxysmal nocturnal hemoglobinuria. Has a functional binding affinity to erythrocytes of 8.7 x 107 M-1. The antigen is pronase and trypsin resistant and chymotrypsin sensitive. Recognizes the consensus region 3 of the DAF molecule, which contains the functional site, and the antibody blocks the function of DAF.

Purification: Protein G purified

Immunogen: Human fibroblast cell line.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, IP

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL Method sheets are available on request.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: deionized water

Concentration: Lot specific

Buffer: 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Alternative Name: CD55

Background: Name/Gene ID: CD55

Synonyms: CD55, CD55 antigen, Decay-accelerating factor, TC, CR, CROM, DAF

Gene ID: 1604

UniProt: P08174

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity