BAF53A antibody (AA 331-406)

Catalog No. ABIN2170317

This anti-BAF53A antibody is a Rabbit Polyclonal antibody detecting BAF53A in WB, ELISA and IHC (p). Suitable for Mouse.

Quick Overview for BAF53A antibody (AA 331-406) (ABIN2170317)

Target: BAF53A (Actin-Like 6A (BAF53A))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAF53A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BAF53A Antibody

Binding Specificity: AA 331-406

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANGPTL4/ARP4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BAF53A

Target: BAF53A (Actin-Like 6A (BAF53A))

Alternative Name: ARP4

Background:

Synonyms: Angiopoietin like 4, Angiopoietin related protein 4, Angiopoietin-like protein 4, Angiopoietin-related protein 4, Angiopoietin-like 4, ANGL4_HUMAN, ANGPT L2, ANGPT L4, ANGPTL2, ANGPTL4, ARP4, Fasting induced adipose factor, FIAF, Hepatic angiopoietin related protein, Hepatic fibrinogen/angiopoietin related protein, Hepatic fibrinogen/angiopoietin-related protein, HFARP, NL2, Peroxisome prolerator-activated receptor PPAR gamma induced angiopoietin related protein antibody PGAR, pp1158, PPARG angiopoietin related protein, PSEC0166, Weakly similar to angiopoietin 1 [H.sapiens].

Background: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorgenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

Gene ID: 51129

Pathways: Chromatin Binding, Photoperiodism