ICAM2 antibody

Catalog No. ABIN217706

Product Details anti-ICAM2 Antibody

Target: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ICAM2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Specificity: Recognizes murine intercellular adhesion molecule-2 (ICAM-2), also known as CD102. Murine CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is constitutively expressed on endothelial cells. CD102 interacts with the CD11a/CD18 integrin LFA-1. Reports suggest that CD102 may play a role in lymphocyte re-circulation and T-cell activation. Clone mIC2/4 is reported to inhibit interactions between CD102 and LFA-1(1).

Purification: Protein G purified

Endotoxin Level: Low Endotoxin

Immunogen: COS cells transfected with murine ICAM-2.

Type of Immunogen: Cells

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo (1:50 - 1:200), Func, IP

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6cells in 100 μL. Method sheets are available on request.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4.

Target Details for ICAM2

Target: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Alternative Name: ICAM2 / CD102 (ICAM2 Products)

Background: Name/Gene ID: ICAM2
Family: ICAM

Synonyms: ICAM2, CD102, ICAM-2, CD102 antigen

Gene ID: 3384