KLHL20 antibody (PE)

Catalog No. ABIN2177162

The Rabbit Polyclonal anti-KLHL20 antibody is suitable to detect KLHL20 in samples from Human, Rat and Mouse. It has been validated for FACS.

Quick Overview for KLHL20 antibody (PE) (ABIN2177162)

Target: KLHL20 (Kelch-Like 20 (KLHL20))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHL20 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-KLHL20 Antibody (PE)

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KLHL20

Isotype: IgG

Application Details

Application Notes: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4 °C for 12 months.

Target Details for KLHL20

Target: KLHL20 (Kelch-Like 20 (KLHL20))

Alternative Name: Klhl20

Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis. Also acts as a regulator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases.
Synonyms: Kelch like ECT2 interacting protein, Kelch like protein 20, Kelch like protein X, Kelch mot containing protein, Kelch-like ECT2-interacting protein, Kelch-like protein 20, Kelch-like protein X, KHLHX, KLEIP, KLH20_HUMAN, KLHL20, KLHLX, RP3-383J4.3.

Gene ID: 27252