KLHL20 antibody (PE)
Quick Overview for KLHL20 antibody (PE) (ABIN2177162)
Target
See all KLHL20 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human KLHL20
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Isotype
- IgG
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Application Notes
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FCM: (1:20-100)
Optimal working dilution should be determined by the investigator. -
Comment
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Exitation/Emission: 480,565nm/578nm
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at 4 °C for 12 months.
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- KLHL20 (Kelch-Like 20 (KLHL20))
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Alternative Name
- Klhl20
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Background
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Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis. Also acts as a regulator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases.
Synonyms: Kelch like ECT2 interacting protein, Kelch like protein 20, Kelch like protein X, Kelch mot containing protein, Kelch-like ECT2-interacting protein, Kelch-like protein 20, Kelch-like protein X, KHLHX, KLEIP, KLH20_HUMAN, KLHL20, KLHLX, RP3-383J4.3. -
Gene ID
- 27252
Target
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