SYCP3 antibody (PE)

Catalog No. ABIN2179079

The Rabbit Polyclonal anti-SYCP3 antibody has been validated for WB. It is suitable to detect SYCP3 in samples from Human, Mouse and Rat.

Quick Overview for SYCP3 antibody (PE) (ABIN2179079)

Target: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYCP3 antibody is conjugated to PE

Application: Western Blotting (WB)

Product Details anti-SYCP3 Antibody (PE)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CTDSPL

Isotype: IgG

Application Details

Application Notes: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Target Details for SYCP3

Target: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Alternative Name: Scp3

Background:

Synonyms: PSR1, SCP3, HYA22, RBSP3, C3orf8, CTD small phosphatase-like protein, CTDSP-like, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3, NIF-like protein, Nuclear LIM interactor-interacting factor 1, NLI-interacting factor 1, Protein YA22, Small C-terminal domain phosphatase 3, Small CTD phosphatase 3, CTDSPL, NIF1, NIFL, YA22

Background: Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity). Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.

Gene ID: 10217

UniProt: O15194