Smith Antigen antibody
Quick Overview for Smith Antigen antibody (ABIN238115)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity (Details)
- Shows the Sm precipitate band when tested using double immunodiffusion against rabbit thymus extract. Specificity is verified by identity of precipitation with CDC-AF reference serum. Anti-RNP precipitant is also detected. Titer will vary with test system, however, undiluted antibody shows a strong Sm precipitate band. Exhibits no reactivity at a dilution of 1:100 when tested against purified SSB, Scl-70 and Jo-1 antigens in an ELISA system designed to detect all IgG subclasses. Anti-RNP and low levels of anti-SSA activity are detected in this ELISA system.
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Characteristics
- Human anti Sm antigen Human antibody to Sm (Smith) antigen
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Purification
- Single donor human plasma is delipidized and defibrinated. An immunoglobulin fraction is then precipitated and collected. Human plasma
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Application Notes
- Suitable for use in Immunodiffusion and ELISA. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
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Comment
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Reconstitute with 2ml deionized water.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from 0.01 M Phosphate, 0.11 M Sodium chloride, pH 7.2, 0.02 % Sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
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Avoid multiple freeze/thaw cycles.
Centrifuge product if not completely clear after standing at room temperature.
Prepare working dilution only prior to immediate use. -
Storage
- 0 °C
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Storage Comment
- Store at < 0 °C.
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- Smith Antigen
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Alternative Name
- Sm (Smith) Antigen
Target
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