GTF2I antibody
Quick Overview for GTF2I antibody (ABIN2460315)
Target
See all GTF2I AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Antibody is purified by peptide affinity chromatography method.
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Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GTF2I.
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Application Notes
- GTF2I antibody can be used for detection of GTF2I by ELISA at 1:62500. GTF2I antibody can be used for detection of GTF2I by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Concentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store GTF2I antibody at -20 °C.
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- GTF2I (General Transcription Factor III (GTF2I))
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Alternative Name
- GTF2I
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Background
- GTF2I encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon (s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants.
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Molecular Weight
- 110 kDa
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Gene ID
- 2969
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NCBI Accession
- NP_127493
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UniProt
- Q75M86
Target
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