SHOX2 antibody

Catalog No. ABIN2460684

Product Details anti-SHOX2 Antibody

Target: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Reactivity: Human, Rat, Mouse, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHOX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SHOX2.

Application Details

Application Notes: SHOX2 antibody can be used for detection of SHOX2 by ELISA at 1:62500. SHOX2 antibody can be used for detection of SHOX2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SHOX2 antibody at -20 °C.

Target Details for SHOX2

Target: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Alternative Name: SHOX2 (SHOX2 Products)

Background: SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients.

Molecular Weight: 35 kDa

Gene ID: 6474

NCBI Accession: NP_006875

UniProt: O60902

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development