DPYS antibody
Quick Overview for DPYS antibody (ABIN2462415)
Target
See all DPYS AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Antibody is purified by protein A chromatography method.
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Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DPYS.
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Application Notes
- DPYS antibody can be used for detection of DPYS by ELISA at 1:312500. DPYS antibody can be used for detection of DPYS by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Concentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store DPYS antibody at -20 °C.
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- DPYS (Dihydropyrimidinase (DPYS))
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Alternative Name
- DPYS
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Background
- Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.
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Molecular Weight
- 56 kDa
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Gene ID
- 1807
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NCBI Accession
- NP_001376
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UniProt
- Q14117
Target
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