ADAM33 antibody

Catalog No. ABIN2463304

This Rabbit Polyclonal antibody specifically detects ADAM33 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ADAM33 antibody (ABIN2463304)

Target: ADAM33 (ADAM Metallopeptidase Domain 33 (ADAM33))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM33 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ADAM33 Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ADAM33.

Application Details

Application Notes: ADAM33 antibody can be used for detection of ADAM33 by ELISA at 1:1562500. ADAM33 antibody can be used for detection of ADAM33 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ADAM33 antibody at -20 °C.

Target Details for ADAM33

Target: ADAM33 (ADAM Metallopeptidase Domain 33 (ADAM33))

Alternative Name: ADAM33

Background: ADAM33 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM33 is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Molecular Weight: 62 kDa

Gene ID: 80332

NCBI Accession: NP_079496

UniProt: Q9BZ11