Transcription factor E3 antibody can be used for the detection of Transcription factor E3 by Western Blot.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate-Buffered Saline. No preservatives added.
Preservative
Without preservative
Handling Advice
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage
4 °C/-20 °C
Storage Comment
TFE3 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
Target
TFE3
(Transcription Factor E3 (TFE3))
Alternative Name
TFE3
Background
FUNCTION: Positive-acting transcription factor that binds to the immunoglobulin enchancer MUE3 motif. It binds also very well to a USF/MLTF site. Binding of TFE3 to DNA induces DNA binding.
DISEASE: Chromosomal aberrations involving TFE3 may be a cause of papillary renal cell carcinoma (PRCC). Translocation t(X,1)(p11.2,q21.2) with PRCC, translocation t(X,1)(p11.2,p34) with PSF, inversion inv(X)(p11.2,q12) that fuses NONO to TFE3.